But in my opinion, chances are the impact will be minimal. Looking at previous key infections of the century: Blaster, Netsky & Sasser, Melissa virus, ILOVEYOU and Anna Kournikova worm. What does it tell you?
The highest impact rate were not recorded on the day it was predicted to be active, but mostly after. (when people's guard were down)
Here're some Q&A from Symantec on how to get yourself protected.